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Mouse hepatitis virus and herpes simplex virus move along different CNS pathways. Adv Exp Med Biol 1993;342:313-8

Date

01/01/1993

Pubmed ID

7516106

DOI

10.1007/978-1-4615-2996-5_48

Scopus ID

2-s2.0-0028211650 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

The spread of mouse hepatitis virus, strain JHM and herpes simplex virus type 1 in the central nervous system after inoculation into the nares and main olfactory bulb has been examined. The results show that each virus infects a subset of the possible connections of the olfactory bulb and that the subset infected by each virus is different. Thus, both viruses will be useful for studying the neuroanatomic connections of the olfactory bulb, and possibly for functional analyses as well.

Author List

Perlman S, Barnett E, Jacobsen G

Author

Edward M. Barnett MD, PhD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Administration, Intranasal
Animals
Axonal Transport
Brain
Dental Pulp
Injections
Locus Coeruleus
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Murine hepatitis virus
Olfactory Bulb
Olfactory Pathways
Simplexvirus
Species Specificity
Specific Pathogen-Free Organisms
Trigeminal Nerve