Antibiotic sensitivity and resistance patterns in pediatric staphylococcal scalded skin syndrome. Pediatr Dermatol 2014;31(3):305-8
Date
09/17/2013Pubmed ID
24033633Pubmed Central ID
PMC4349361DOI
10.1111/pde.12195Scopus ID
2-s2.0-84899503143 (requires institutional sign-in at Scopus site) 48 CitationsAbstract
Historical resistance patterns often guide empiric antibiotic choices in staphylococcal scalded skin syndrome (SSSS), but little is known about the difference in susceptibility between SSSS and other childhood staphylococcal infections. A retrospective chart review of culture-confirmed cases of SSSS seen in the inpatient dermatology consultation service at the Children's Hospital of Philadelphia between 2005 and 2011 was performed. Most cases of SSSS at our institution are due to oxacillin-susceptible Staphylococcus aureus, and approximately half of the cases are due to clindamycin-resistant strains. Clindamycin and a penicillinase-resistant penicillin are suggested as empiric treatment for SSSS until culture susceptibility data are available to guide therapy.
Author List
Braunstein I, Wanat KA, Abuabara K, McGowan KL, Yan AC, Treat JRAuthor
Karolyn A. Wanat MD Chair, Professor in the Dermatology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anti-Bacterial AgentsChild, Preschool
Clindamycin
Drug Resistance, Bacterial
Female
Hospitals, Pediatric
Humans
Infant
Male
Oxacillin
Penicillinase
Philadelphia
Retrospective Studies
Staphylococcal Scalded Skin Syndrome
Staphylococcus aureus
