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Sexual health in hematopoietic stem cell transplant recipients. Cancer 2015 Dec 01;121(23):4124-31

Date

09/16/2015

Pubmed ID

26372459

Pubmed Central ID

PMC5014908

DOI

10.1002/cncr.29675

Scopus ID

2-s2.0-84948569699 (requires institutional sign-in at Scopus site)   43 Citations

Abstract

Hematopoietic stem cell transplantation (HSCT) plays a central role in patients with malignant and, increasingly, nonmalignant conditions. As the number of transplants increases and the survival rate improves, long-term complications are important to recognize and treat to maintain quality of life. Sexual dysfunction is a commonly described but relatively often underestimated complication after HSCT. Conditioning regimens, generalized or genital graft-versus-host disease, medications, and cardiovascular complications as well as psychosocial problems are known to contribute significantly to physical and psychological sexual dysfunction. Moreover, it is often a difficult topic for patients, their significant others, and health care providers to discuss. Early recognition and management of sexual dysfunction after HSCT can lead to improved quality of life and outcomes for patients and their partners. This review focuses on the risk factors for and treatment of sexual dysfunction after transplantation and provides guidance concerning how to approach and manage a patient with sexual dysfunction after HSCT.

Author List

Li Z, Mewawalla P, Stratton P, Yong AS, Shaw BE, Hashmi S, Jagasia M, Mohty M, Majhail NS, Savani BN, Rovó A

Author

Bronwen E. Shaw MBChB, PhD Center Director, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Disease Management
Female
Graft vs Host Disease
Health Personnel
Hematopoietic Stem Cell Transplantation
Humans
Male
Practice Guidelines as Topic
Quality of Life
Reproductive Health
Risk Factors
Sexual Dysfunction, Physiological
Sexual Dysfunctions, Psychological
Spouses
Transplantation Conditioning