Arrhythmias in Adult Congenital Patients With Bodily Isomerism. Pediatr Cardiol 2016 Feb;37(2):330-7
Date
10/21/2015Pubmed ID
26481118DOI
10.1007/s00246-015-1281-7Scopus ID
2-s2.0-84959128917 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
There are an increasing number of adults with congenital heart disease, some of whom have bodily isomerism. Bodily isomerism or heterotaxy is a unique clinical entity associated with congenital malformations of the heart which further increases the risk for future cardiovascular complications. We aimed to investigate the frequency of arrhythmias in adults with bodily isomerism. We utilized the 2012 iteration of the Nationwide Inpatient Sample to identify adult inpatient admissions associated with arrhythmias in patients with isomerism. Data regarding demographics, comorbidities, and various procedures were collected and compared between those with and without isomerism. A total of 6,907,109 admissions were analyzed with a total of 861 being associated isomerism. The frequency of arrhythmias was greater in those with isomerism (20.8 vs. 15.4 %). Those with isomerism were also more five times more likely to undergo invasive electrophysiology studies. Length and cost of hospitalization for patients with arrhythmias also tended to be greater in those with isomerism. Mortality did not differ between the two groups. Arrhythmias are more prevalent in those with isomerism, with a majority of arrhythmias in isomerism being atrial. Those with isomerism and arrhythmias also tended to have greater length and cost of hospitalization.
Author List
Loomba RS, Aggarwal S, Gupta N, Buelow M, Alla V, Arora RR, Anderson RHAuthor
Matthew W. Buelow MD Associate Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Arrhythmias, Cardiac
Child
Child, Preschool
Databases, Factual
Electrocardiography
Female
Heart
Heterotaxy Syndrome
Humans
Infant
Infant, Newborn
Logistic Models
Male
Middle Aged
Multivariate Analysis
United States
Young Adult
