Faculty Collaboration Database

Management of suspected adrenal metastases at 2 academic medical centers. Am J Surg 2016 Apr;211(4):664-70

Date

01/30/2016

Pubmed ID

26822269

DOI

10.1016/j.amjsurg.2015.11.019

Scopus ID

2-s2.0-84955577001 (requires institutional sign-in at Scopus site)   20 Citations

Abstract

BACKGROUND: The optimal management of suspected adrenal metastases remains controversial.

METHODS: This is a retrospective bi-institutional review of 37 patients who underwent adrenalectomy for suspected adrenal metastasis between 2001 and 2014.

RESULTS: Three (8%) patients had benign adenomas on final pathology. At a median follow-up of 21 months, 7 (32%) patients were alive with no evidence of disease and 7 (32%) were alive with recurrent disease. Recurrence-free survival (RFS) was 8 months; decreased RFS was associated with positive margins and size ≥6 cm. Overall survival (OS) was 29 months; decreased OS was associated with capsular disruption. There were no differences in RFS or OS by surgical approach.

CONCLUSIONS: The favorable OS supports adrenalectomy in select patients with suspected adrenal metastases. Minimally invasive adrenalectomy is safe and effective, but the surgical approach should be based on the ability to achieve a margin-negative resection with avoidance of capsular disruption.

Author List

Glenn JA, Kiernan CM, Yen TW, Solorzano CC, Carr AA, Evans DB, Wang TS

Authors

Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of Wisconsin
Tracy S. Wang MD, MPH Professor in the Surgery department at Medical College of Wisconsin
Tina W F Yen MD, MS Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Academic Medical Centers
Adrenal Gland Neoplasms
Adrenalectomy
Aged
Diagnostic Imaging
Female
Humans
Image-Guided Biopsy
Laparoscopy
Male
Middle Aged
Neoplasm Recurrence, Local
Neoplasm Staging
Retrospective Studies
Survival Rate
Treatment Outcome