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High Prevalence of Nausea among School Children in Latin America. J Pediatr 2016 Feb;169:98-104.e1



Pubmed ID




Scopus ID

2-s2.0-84959258039 (requires institutional sign-in at Scopus site)   16 Citations


OBJECTIVES: To evaluate the prevalence of nausea and its association with functional gastrointestinal disorders (FGIDs) in a large-scale, population-based study of Latin American school children.

STUDY DESIGN: This cross-sectional study collected data from children in 3 Latin American countries. A Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-III) was administered to school children in Central and South America. Subjects were classified into FGIDs based on Rome criteria (QPGS-III). Students from 4 public and 4 private schools in the countries of El Salvador, Panama, and Ecuador participated in this epidemiologic study.

RESULTS: A total of 1137 school children with mean age 11.5 (SD 1.9, range 8-15) years completed the QPGS-III (El Salvador n = 399; Panama n = 321; Ecuador n = 417). Nausea was present in 15.9% of all school children. Two hundred sixty-eight (24%) children met criteria for at least 1 FGID. Nausea was significantly more common in children with FGIDs compared with those without: El Salvador 38% vs 15% (P < .001); Panama 22% vs 7% (P < .001); Ecuador 25% vs 13% (P = .004). Among children with FGIDs, those with functional constipation had a high prevalence of nausea. Nausea was significantly more common in girls and children attending private schools.

CONCLUSIONS: Nausea is commonly present in Latin American school children. FGIDs are frequently associated with nausea.

Author List

Saps M, Velasco-Benítez C, Kovacic K, Chelimsky G, Kovacic K, Játiva Mariño E, Chanís R, Zablah R


Katja K. Karrento MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Karlo Kovacic MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Cross-Sectional Studies
El Salvador
Gastrointestinal Diseases