Medical College of Wisconsin
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Pediatric Vascular Tumors and Malformations. Surg Pathol Clin 2010 Sep;3(3):455-94



Pubmed ID




Scopus ID

2-s2.0-77958122818 (requires institutional sign-in at Scopus site)   47 Citations


Pediatric vascular tumors and malformations, comprising a broad category of lesions often referred to as vascular anomalies, are a heterogenous group of clinicopathologically distinct entities. Pathologists, clinicians, and radiologists have traditionally lumped these lesions under the generic term, hemangioma, sometimes qualified by modifiers, such as capillary or cavernous. Advances in understanding underlying pathogenetic mechanisms support more specific classification and more specifically targeted therapies. Multidisciplinary consensus has moved toward a biologically based classification system and therapeutic approach for dealing with these lesions. This content focuses on the histologic, immunophenotypical, and clinical features that distinguish the major types of vascular tumors and malformations presenting in infancy and childhood. Pathogenic mechanisms are also briefly reviewed.

Author List

North PE


Paula E. North MD, PhD Professor in the Pathology department at Medical College of Wisconsin