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Candida keratitis after descemet stripping and automated endothelial keratoplasty. Cornea 2009 May;28(4):471-3

Date

05/05/2009

Pubmed ID

19411972

DOI

10.1097/ICO.0b013e31818ad9bc

Scopus ID

2-s2.0-67650571774 (requires institutional sign-in at Scopus site)   50 Citations

Abstract

PURPOSE: To report the donor-to-host transmission of Candida albicans after Descemet stripping and automated endothelial keratoplasty (DSAEK).

METHODS: An 80-year-old woman with pseudophakic bullous keratopathy developed an infiltrate in the donor corneal lenticule after DSAEK.

RESULTS: Donor corneoscleral rim cultures grew C. albicans. Gram stain of the removed corneal lenticule demonstrated budding yeast and pseudohyphae, and cultures yielded C. albicans. Despite topical and systemic antifungal therapy and therapeutic penetrating keratoplasty, the patient developed a blind painful eye and underwent enucleation.

CONCLUSIONS: This case report indicates that fungal keratitis may occur from donor-to-host transmission after DSAEK. The location of the infected tissue poses diagnostic and therapeutic challenges for the surgeon.

Author List

Koenig SB, Wirostko WJ, Fish RI, Covert DJ

Author

William Wirostko MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged, 80 and over
Candida albicans
Candidiasis
Cornea
Corneal Transplantation
Descemet Membrane
Disease Transmission, Infectious
Endothelium, Corneal
Eye Infections, Fungal
Female
Humans
Keratitis
Keratoplasty, Penetrating
Tissue Donors