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Cardiorespiratory events in extremely low birth weight infants: neurodevelopmental outcome at 1 and 2 years. J Perinatol 2014 Jul;34(7):562-5

Date

03/22/2014

Pubmed ID

24651731

DOI

10.1038/jp.2014.44

Abstract

OBJECTIVE: To examine the association between cardiorespiratory events (CRE) and neurodevelopmental (ND) outcome at 8 and 20 months corrected age (CA) in a contemporary extremely low birth weight (ELBW )cohort.

STUDY DESIGN: Retrospective chart review of 98 ELBW infants born in 2009 to 2010 who completed ND assessments at 8 and 20 months CA. Neonatal, sociodemographic, CRE and ND data were collected. ND outcome measures included neurologic examination and results from the Bayley Scales of Infant and Toddler Development-III. Multiple regression analyses adjusted for the impact of neonatal risk factors on ND outcome.

RESULT: After adjusting for neonatal and social variables, greater frequency of CRE was related to worse language scores at 8 months, while CRE of greater severity were related to worse language at 20 months CA.

CONCLUSION: CRE in ELBW infants have impact on language development in the first two years of life.

Author List

Greene MM, Patra K, Khan S, Karst JS, Nelson MN, Silvestri JM

Author

Jeffrey S. Karst PhD Assistant Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Apnea
Bradycardia
Child Development
Cohort Studies
Developmental Disabilities
Female
Humans
Infant
Infant, Extremely Low Birth Weight
Infant, Newborn
Language Development
Male
Neurologic Examination
Regression Analysis
Retrospective Studies
Risk Factors