Relation of mucous membrane alterations to oral intake during the first year after treatment for head and neck cancer. Head Neck 2011 Jun;33(6):774-9
Date
08/26/2010Pubmed ID
20737496Pubmed Central ID
PMC4061735DOI
10.1002/hed.21542Scopus ID
2-s2.0-79955917290 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
BACKGROUND: Acute oral mucositis is associated with pain and impaired swallowing. Little information is available on the effects of chronic mucositis on swallowing.
METHODS: Sixty patients treated for cancer of the head and neck were examined during the first year after their cancer treatment. Oral mucosa was rated with the Oral Mucositis Assessment Scale. Stimulated whole-mouth saliva, oral pain rating, percent of oral intake, and 2 subscales of the Performance Status Scale for Head and Neck (PSS-HN) cancer were also collected.
RESULTS: Mucositis scores and pain ratings decreased over time while functional measures of eating improved over time. Reduction in chronic mucositis was correlated with improved oral intake and diet.
CONCLUSION: Lack of association with pain was attributed to the absence of ulcerations. Continued impairment of oral intake during the first year posttreatment may be related to oral mucosal changes and other factors.
Author List
Pauloski BR, Rademaker AW, Logemann JA, Lundy D, Bernstein M, McBreen C, Santa D, Campanelli A, Kelchner L, Klaben B, Discekici-Harris MAuthor
Barbara R. Pauloski PhD, CCC-SLP Associate Professor in the Communication Sciences & Disorders department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AdultAftercare
Aged
Chemotherapy, Adjuvant
Cohort Studies
Combined Modality Therapy
Deglutition
Deglutition Disorders
Diet
Eating
Female
Follow-Up Studies
Head and Neck Neoplasms
Humans
Male
Middle Aged
Mouth Mucosa
Mucositis
Neck Dissection
Neoplasm Staging
Pain
Pain Measurement
Radiotherapy, Adjuvant
Risk Assessment
Time Factors
Treatment Outcome
Young Adult