Swallowing disorders in the first year after radiation and chemoradiation. Head Neck 2008 Feb;30(2):148-58
Date
09/06/2007Pubmed ID
17786992Pubmed Central ID
PMC2903205DOI
10.1002/hed.20672Scopus ID
2-s2.0-39149100321 (requires institutional sign-in at Scopus site) 159 CitationsAbstract
BACKGROUND: Radiation alone or concurrent chemoradiation can result in severe swallowing disorders. This manuscript defines the swallowing disorders occurring at pretreatment and 3 and 12 months after completion of radiation or chemoradiation.
METHODS: Forty-eight patients (10 women and 38 men) participated in this study involving videofluorographic evaluation of oropharyngeal swallow at the 3 time points.
RESULTS: At baseline, patients had some swallow disorders, probably related to presence of their tumor. At 3 months posttreatment, frequency of reduced tongue base retraction, slow or delayed laryngeal vestibule closure, and reduced laryngeal elevation increased from baseline. Some disorders continued at 12 months posttreatment. Functional swallow decreased over time in patients treated with chemoradiation, but not those treated with radiation alone.
DISCUSSION: Chemoradiation results in fewer functional swallowers than radiation alone at 12 months posttreatment completion.
Author List
Logemann JA, Pauloski BR, Rademaker AW, Lazarus CL, Gaziano J, Stachowiak L, Newman L, MacCracken E, Santa D, Mittal BAuthor
Barbara R. Pauloski PhD, CCC-SLP Associate Professor in the Communication Sciences & Disorders department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AdultAged
Combined Modality Therapy
Deglutition Disorders
Female
Fluoroscopy
Head and Neck Neoplasms
Humans
Laryngeal Neoplasms
Male
Middle Aged
Oropharyngeal Neoplasms
Prospective Studies
Radiotherapy
Radiotherapy Dosage
