Faculty Collaboration Database

Evaluation of the Intermittent Exotropia Questionnaire using Rasch analysis. JAMA Ophthalmol 2015 Apr;133(4):461-5

Date

01/31/2015

Pubmed ID

25634146

Pubmed Central ID

PMC4393341

DOI

10.1001/jamaophthalmol.2014.5622

Scopus ID

2-s2.0-84928248681 (requires institutional sign-in at Scopus site)   21 Citations

Abstract

IMPORTANCE: The Intermittent Exotropia Questionnaire (IXTQ) is a patient, proxy, and parental report of quality of life specific to children with intermittent exotropia. We refine the IXTQ using Rasch analysis to improve reliability and validity.

OBSERVATION: Rasch analysis was performed on responses of 575 patients with intermittent exotropia enrolled from May 15, 2008, through July 24, 2013, and their parents from each of the 4 IXTQ health-related quality-of-life questionnaires (child 5 through 7 years of age and child 8 through 17 years of age, proxy, and parent questionnaires). Questionnaire performance and structure were confirmed in a separate cohort of 379 patients with intermittent exotropia. One item was removed from the 12-item child and proxy questionnaires, and response options in the 8- to 17-year-old child IXTQ and proxy IXTQ were combined into 3 response options for both questionnaires. Targeting was relatively poor for the child and proxy questionnaires. For the parent questionnaire, 3 subscales (psychosocial, function, and surgery) were evident. One item was removed from the psychosocial subscale. Resulting subscales had appropriate targeting.

CONCLUSIONS AND RELEVANCE: The Rasch-revised IXTQ may be a useful instrument for determining how intermittent exotropia affects health-related quality of life of children with intermittent exotropia and their parents, particularly for cohort studies.

Author List

Leske DA, Holmes JM, Melia BM, Pediatric Eye Disease Investigator Group

Author

Alexander Joseph Khammar MD Associate Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Child
Child, Preschool
Cross-Sectional Studies
Exotropia
Female
Health Status
Humans
Infant
Male
Quality of Life
Reproducibility of Results
Sickness Impact Profile
Surveys and Questionnaires