Faculty Collaboration Database

Pediatric Contact Dermatitis Registry Inaugural Case Data. Dermatitis 2016;27(5):293-302

Date

09/21/2016

Pubmed ID

27649353

DOI

10.1097/DER.0000000000000214

Scopus ID

2-s2.0-84988647940 (requires institutional sign-in at Scopus site)   46 Citations

Abstract

BACKGROUND: Little is known about the epidemiology of allergic contact dermatitis (ACD) in US children. More widespread diagnostic confirmation through epicutaneous patch testing is needed.

OBJECTIVE: The aim was to quantify patch test results from providers evaluating US children.

METHODS: The study is a retrospective analysis of deidentified patch test results of children aged 18 years or younger, entered by participating providers in the Pediatric Contact Dermatitis Registry, during the first year of data collection (2015-2016).

RESULTS: One thousand one hundred forty-two cases from 34 US states, entered by 84 providers, were analyzed. Sixty-five percent of cases had one or more positive patch test (PPT), with 48% of cases having 1 or more relevant positive patch test (RPPT). The most common PPT allergens were nickel (22%), fragrance mix I (11%), cobalt (9.1%), balsam of Peru (8.4%), neomycin (7.2%), propylene glycol (6.8%), cocamidopropyl betaine (6.4%), bacitracin (6.2%), formaldehyde (5.7%), and gold (5.7%).

CONCLUSIONS: This US database provides multidisciplinary information on pediatric ACD, rates of PPT, and relevant RPPT reactions, validating the high rates of pediatric ACD previously reported in the literature. The registry database is the largest comprehensive collection of US-only pediatric patch test cases on which future research can be built. Continued collaboration between patients, health care providers, manufacturers, and policy makers is needed to decrease the most common allergens in pediatric consumer products.

Author List

Goldenberg A, Mousdicas N, Silverberg N, Powell D, Pelletier JL, Silverberg JI, Zippin J, Fonacier L, Tosti A, Lawley L, Wu Chang M, Scheman A, Kleiner G, Williams J, Watsky K, Dunnick CA, Frederickson R, Matiz C, Chaney K, Estes TS, Botto N, Draper M, Kircik L, Lugo-Somolinos A, Machler B, Jacob SE

Author

Keri S. Chaney MD Assistant Professor in the Dermatology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Allergens
Bacitracin
Balsams
Betaine
Child
Child, Preschool
Cobalt
Dermatitis, Allergic Contact
Female
Formaldehyde
Gold
Humans
Infant
Infant, Newborn
Male
Neomycin
Nickel
Patch Tests
Perfume
Propylene Glycol
Registries
Retrospective Studies
United States