Faculty Collaboration Database

Predictors of HIV Care Engagement, Antiretroviral Medication Adherence, and Viral Suppression Among People Living with HIV Infection in St. Petersburg, Russia. AIDS Behav 2018 Mar;22(3):791-799

Date

12/19/2016

Pubmed ID

27990579

Pubmed Central ID

PMC5476511

DOI

10.1007/s10461-016-1638-9

Scopus ID

2-s2.0-85006355938 (requires institutional sign-in at Scopus site)   31 Citations

Abstract

Over 1 million HIV infections have been diagnosed in Russia, and HIV care uptake and viral suppression are very low. 241 HIV-positive individuals in St. Petersburg were enrolled through social networks, provided blood for viral load testing, and completed measures of medication-taking adherence, readiness, and self-efficacy; psychosocial well-being; and substance use. Outcomes included attending an HIV care appointment in the past 6 months, >90% ART adherence, and undetectable viral load. 26% of participants had no recent care appointment, 18% had suboptimal adherence, and 56% had detectable viral load. Alcohol use consistently predicted all adverse health outcomes. Having no recent care visit was additionally associated with being single and greater past-month drug injection frequency. Poor adherence was additionally predicted by lower medication-taking self-efficacy and lower anxiety. Detectable viral load was additionally related to younger age. Comprehensive interventions to improve HIV care in Russia must address substance abuse, anxiety, and medication-taking self-efficacy.

Author List

Amirkhanian YA, Kelly JA, DiFranceisco WJ, Kuznetsova AV, Tarima SS, Yakovlev AA, Musatov VB

Authors

Yuri A. Amirkhanian PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin
Wayne J. DiFranceisco Research Scientist II in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin
Jeffrey A. Kelly PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin
Sergey S. Tarima PhD Associate Professor in the Data Science Institute department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Anti-Retroviral Agents
Anxiety
Continuity of Patient Care
Female
HIV Infections
Humans
Male
Medication Adherence
Middle Aged
Risk-Taking
Russia
Self Efficacy
Substance-Related Disorders
Viral Load