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Depressive symptoms, serious psychological distress, diabetes distress and cardiovascular risk factor control in patients with type 2 diabetes. J Diabetes Complications 2016 Mar;30(2):312-7

Date

12/15/2015

Pubmed ID

26657725

Pubmed Central ID

PMC4761313

DOI

10.1016/j.jdiacomp.2015.11.010

Scopus ID

2-s2.0-84949666509 (requires institutional sign-in at Scopus site)   31 Citations

Abstract

OBJECTIVE: This study examined the association between cardiovascular disease (CVD) risk factor control and elevated depressive symptoms (EDS), serious psychological distress (SPD), and diabetes distress (DD) in patients with type 2 diabetes (T2DM).

METHODS: This was a cross-sectional study of adults seen at an academic medical center and Veterans Affairs Medical Center in the southeastern US. Linear regression models were computed using CVD risk factors as clinically meaningful outcomes (glycosylated hemoglobin A1c (HbA1c); systolic (SBP) and diastolic (DBP) blood pressure; and low-density lipoprotein cholesterol (LDL-C)); EDS, SPD, and DD were primary independent variables. Covariates included sociodemographics and comorbidities.

RESULTS: The sample consisted of 361 adults. Correlation analyses showed significant relationships between DD and HbA1c, DBP, and LDL-C. Adjusted linear regression models showed DD to be significantly associated with HbA1c and LDL-C, and SPD to be significantly associated only with LDL-C. In the fully adjusted model, DD remained significantly associated with HbA1c (β=4.349; 95% CI (-0.649, 2.222)).

CONCLUSIONS: In this sample of adults with T2DM, DD and SPD were significantly associated with CVD risk factors; however, after controlling for covariates, only DD was shown to be significantly associated with poor glycemic control.

PRACTICE IMPLICATIONS: Strategies are warranted to examine the relationship between DD and CVD risk factor control in patients with T2DM.

Author List

Winchester RJ, Williams JS, Wolfman TE, Egede LE

Authors

Leonard E. Egede MD Center Director, Chief, Professor in the Medicine department at Medical College of Wisconsin
Joni Williams MD, MPH Associate Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Aged, 80 and over
Cardiovascular Diseases
Cross-Sectional Studies
Depression
Diabetes Mellitus, Type 2
Diabetic Angiopathies
Female
Humans
Male
Middle Aged
Risk Factors
Stress, Psychological
United States
Young Adult