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Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review. Diabetes Manag (Lond) 2014 Jan 01;4(1):29-48

Date

09/13/2014

Pubmed ID

25214893

Pubmed Central ID

PMC4157681

DOI

10.2217/dmt.13.62

Abstract

AIM: Medication adherence is associated with improved outcomes in diabetes. Interventions have been established to help improve medication adherence; however, the most effective interventions in patients with Type 2 diabetes remain unclear. The goal of this study was to distinguish whether interventions were effective and identify areas for future research.

METHODS: Medline was searched for articles published between January 2000 and May 2013, and a reproducible strategy was used. Study eligibility criteria included interventions measuring medication adherence in adults with Type 2 diabetes.

RESULTS: Twenty seven studies met the inclusion criteria and 13 showed a statistically significant change in medication adherence.

CONCLUSION: Heterogeneity of the study designs and measures of adherence made it difficult to identify effective interventions that improved medication adherence. Additionally, medication adherence may not be solely responsible for achieving glycemic control. Researchers must emphasize tailored interventions that optimize management and improve outcomes, and examine the need for clear indicators of medication adherence.

Author List

Williams JL, Walker RJ, Smalls BL, Campbell JA, Egede LE

Authors

Jennifer Annette Campbell PhD, MPH Assistant Professor in the Medicine department at Medical College of Wisconsin
Leonard E. Egede MD Center Director, Chief, Professor in the Medicine department at Medical College of Wisconsin
Rebekah Walker PhD Associate Professor in the Medicine department at Medical College of Wisconsin