Faculty Collaboration Database

The Effect of Obesity on Perioperative Outcomes for Open and Minimally Invasive Prostatectomy. Urology 2017 Feb;100:111-116

Date

11/29/2016

Pubmed ID

27890683

DOI

10.1016/j.urology.2016.11.028

Scopus ID

2-s2.0-85008420001 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

OBJECTIVE: To compare the impact of obesity on perioperative outcomes between open radical prostatectomy (ORP) and minimally invasive prostatectomy (MIP).

METHODS: Using the National Surgical Quality Improvement Program public use files for 2008-2013, we identified patients undergoing prostatectomy using Current Procedural Terminology codes. Those without body mass index (BMI) or comorbidity information were excluded. BMI was treated as a categorical variable according to the World Health Organization classification. Demographic and comorbid conditions were compared between BMI groups, and multivariable logistical regression was used to identify independent predictors of adverse perioperative events.

RESULTS: We identified 17,693 MIP and 4674 ORP for analysis. Of the entire cohort, only 18.7% had a BMI within the normal range (18.5-24.9), whereas the remaining 81.3% were at least overweight (BMI > 25). Class I, II, and III obesity accounted for 25.0%, 7.0%, and 2.3% of the cohort, respectively. Overall, complications were higher with ORP (19.0%) than with MIP (5.3%), which held true across all BMI categories. The rate of wound, renal, thromboembolic, infectious, neurologic, Clavien grade III-V, and overall complications among MIP were directly related to BMI. Only wound and renal complications were related to BMI in ORP. In multivariable analysis, obesity was found to be an independent predictor of wound, renal, and thromboembolic complications.

CONCLUSION: Obesity has a larger impact on morbidity for MIP compared to ORP. Overall morbidity, however, remains lower for MIP across all BMI groups.

Author List

Johnson SC, Packiam VT, Golan S, Cohen AJ, Nottingham CU, Smith ND

Author

Scott C. Johnson MD Associate Professor in the Urologic Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aged
Body Mass Index
Cohort Studies
Humans
Laparoscopy
Length of Stay
Logistic Models
Male
Middle Aged
Obesity
Postoperative Complications
Prostatectomy
Prostatic Neoplasms
Quality Improvement
Treatment Outcome