Solitary plasmacytoma of the lung with light chain extracellular deposits: a case report and review of the literature. Histopathology 1998 Apr;32(4):356-61
Date
05/29/1998Pubmed ID
9602333DOI
10.1046/j.1365-2559.1998.00393.xScopus ID
2-s2.0-0031950222 (requires institutional sign-in at Scopus site) 41 CitationsAbstract
AIMS: We present the clinical and histopathological findings of an unusual pulmonary plasmacytoma associated with light chain deposits.
METHODS AND RESULTS: The tumour was located in the main left stem bronchus 40 mm from the carina. Histologically, it was composed of sheets of well differentiated plasma cells. Large extracellular deposits of amorphous material were observed in the tumour. These deposits were Congo red negative and contained kappa light chains. They were electron dense granular and non-filamentous. No plasmacytosis was identified by bone marrow biopsy and no monoclonal spike was shown by serum and urine electrophoresis.
CONCLUSIONS: Our case is unusual in being endobronchial and showing light chain deposition.
Author List
Piard F, Yaziji N, Jarry O, Assem M, Martin L, Bernard A, Jacquot JP, Justrabo EAuthor
Mahfoud Assem PharmD Associate Professor in the School of Pharmacy Administration department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedHumans
Immunoglobulin kappa-Chains
Immunohistochemistry
In Situ Hybridization
Lung Neoplasms
Male
Microscopy, Electron
Plasmacytoma
Tomography, X-Ray Computed
