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Modified Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy for Hepatoblastoma in a Small Infant: How Far Can We Push the Envelope? Ann Surg 2017 08;266(2):e16-e17

Date

03/14/2017

Pubmed ID

28288067

DOI

10.1097/SLA.0000000000002217

Scopus ID

2-s2.0-85015035612   7 Citations

Abstract

: For patients with hepatoblastoma, a timely and complete resection of the tumor is critical to the patient's tumor recurrence-free survival. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), a 2-stage hepatectomy procedure, has revolutionized the surgical management of large hepatic tumors with insufficient future liver remnant (FLR) at presentation. Although existing data support the utility of ALPPS in adults with primary and metastatic hepatobiliary malignancy, the literature in children is scarce. To our knowledge, this is the first report showing clinical applicability and safety of the modified ALPPS procedure in a small infant (54 days old) with hepatoblastoma who presented with insufficient FLR. Our report suggests the modified ALPPS could potentially expand the surgical treatment alternative for small infants with large hepatoblastoma.

Author List

Hong JC, Kim J, Browning M, Wagner A, Lerret S, Segura AD, Zimmerman MA

Authors

Meghen B. Browning MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Joohyun Kim MD, PhD Associate Professor in the Surgery department at Medical College of Wisconsin
Stacee Lerret PhD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Annette D. Segura MD Assistant Professor in the Pathology department at Medical College of Wisconsin
Amy Wagner MD Associate Professor in the Surgery department at Medical College of Wisconsin
Michael A. Zimmerman MD, FACS Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Hepatectomy
Hepatoblastoma
Humans
Infant
Infant, Newborn
Ligation
Liver Neoplasms
Male
Portal Vein
Treatment Outcome