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Dedifferentiated chondrosarcoma of bone with prominent rhabdoid component. Ann Diagn Pathol 2017 Jun;28:7-11

Date

06/27/2017

Pubmed ID

28648942

DOI

10.1016/j.anndiagpath.2016.11.004

Scopus ID

2-s2.0-85012188149 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

Dedifferentiated chondrosarcomas (DDCS) are rare lesions, defined as tumors having a low-grade chondrosarcomatous component with an abrupt transition to a high-grade sarcoma. Although "malignant fibrous histiocytoma" (undifferentiated pleomorphic sarcoma) is the most common high grade saromatous component, many different types of sarcoma have been described. We present a case of dedifferentiated chondrosarcoma with rhabdomyosarcomatous differentiation harboring a prominent rhabdoid tumor component. To our knowledge, rhabdoid morphology in dedifferentiated chondrosarcoma has not been described in the English-language literature. The pathologic and radiologic features of this case are presented.

Author List

Stemm M, Beck C, Mannem R, Neilson J, Klein MJ

Authors

Rajeev Mannem MD Associate Professor in the Radiology department at Medical College of Wisconsin
John C. Neilson MD Associate Professor in the Orthopaedic Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Bone Neoplasms
Bone and Bones
Cell Differentiation
Chondrosarcoma
Histiocytoma, Malignant Fibrous
Humans
Male
Middle Aged
Tomography, X-Ray Computed