Faculty Collaboration Database

Correlation of Objective Audiometric and Caloric Function in Ménière's Disease. Otolaryngol Head Neck Surg 2017 May;156(5):912-916

Date

02/09/2017

Pubmed ID

28168899

DOI

10.1177/0194599817690103

Scopus ID

2-s2.0-85018740742 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

Objective Ménière's disease affects the vestibular and audiologic systems; however, little is known about the relationship between audiometric and caloric function with increasing duration of disease. We employed a novel methodology to understand the longitudinal correlation between audiometric and caloric function in Ménière's patients. Study Design Case series with chart review. Setting Neuro-otologic tertiary care practice. Subjects and Methods Charts of 19 patients with unilateral Ménière's disease, as classified by the 1995 American Academy of Otolaryngology-Head and Neck Foundation criteria, were examined. We included patients with ≥2 videonystagmograms and audiograms. We excluded those with bilateral Ménière's, prior audiovestibular destruction, or symptoms suggesting concomitant vestibular pathology. Spearman's rank correlation of audiometric status (pure tone average [PTA], low PTA, and word recognition score [WRS]) and vestibular function (bithermal calorics) was performed. The study was Institutional Review Board approved (protocol 2015H0266). Results A total of 112 audiograms and 42 videonystagmographies were performed. There was a decline in affected ear hearing PTA and WRS with duration of disease ( r = 0.602, P < .001, and r = -0.573, P < .001, respectively). Similarly, there was a decline in vestibular function with increasing duration of disease ( r = 0.709, P < .001). There were moderate correlations between vestibular weakness and PTA, low PTA, and WRS ( r = 0.464, P = .002; r = 0.498, P = .001; and r = -0.518, P = .001, respectively). Conclusions There is a correlation between decline in objective hearing and horizontal semicircular canal function with time. As expected, this correlation is not 1:1, indicating differential involvement of both systems. Understanding this relationship may assist in counseling patients with regard to prognosis, natural history, and therapeutic interventions.

Author List

McMullen KP, Lin C, Harris MS, Adunka OF

Author

Michael S. Harris MD Associate Professor in the Otolaryngology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Age Factors
Aged
Audiometry
Audiometry, Evoked Response
Caloric Tests
Cohort Studies
Databases, Factual
Disease Progression
Female
Humans
Male
Meniere Disease
Middle Aged
Retrospective Studies
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index
Sex Factors
Vestibular Evoked Myogenic Potentials