Faculty Collaboration Database

Influence of Posterior Fossa Volume on Clinical Outcomes After Vestibular Schwannoma Resection. Otol Neurotol 2016 Sep;37(8):1155-61

Date

07/01/2016

Pubmed ID

27362739

DOI

10.1097/MAO.0000000000001128

Scopus ID

2-s2.0-84976586548 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

OBJECTIVES: To determine the influence of posterior fossa dimensions on surgical outcomes after vestibular schwannoma management.

STUDY DESIGN: Retrospective chart review.

SETTING: Tertiary care academic medical center.

PATIENTS: Patients with sporadic vestibular schwannomas who underwent surgical resection via retrosigmoid or translabyrinthine techniques.

INTERVENTIONS: Diagnostic.

MAIN OUTCOME MEASURES: One and two-way analysis of variance (ANOVAs) of the cohort based on volumetric and clinical outcome groupings.

RESULTS: A total of 95 patients were identified. A one-way ANOVA looking at the entire cohort of patients showed that outcomes like surgical time (p < 0.001) and whether a Good Outcome (House-Brackmann score of 1 or 2, no complications, and a complete resection) was achieved (p = 0.009) correlated very well with preoperative tumor volume, but not with posterior fossa volume (p = 0.412 and p = 0.345, respectively). However, in medium sized tumors, House-Brackmann group was correlated with posterior fossa volume (p = 0.032).

CONCLUSIONS: The present data suggest a small effect of posterior fossa size on some clinical outcomes in medium sized vestibular schwannomas.

Author List

Macielak RJ, Harris MS, Kirsch CF, Prevedello LM, Adunka OF

Author

Michael S. Harris MD Associate Professor in the Otolaryngology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Female
Humans
Male
Middle Aged
Neuroma, Acoustic
Postoperative Complications
Retrospective Studies
Skull