Faculty Collaboration Database

Helicoid end-to-side and oblique attachment technique in repair of the musculocutaneous nerve injury with the phrenic nerve as a donor: an experimental study in rats. Microsurgery 2011 Feb;31(2):122-9

Date

01/27/2011

Pubmed ID

21268106

DOI

10.1002/micr.20840

Scopus ID

2-s2.0-79751534435 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

The purpose of this study was to identify if a modified end-to-side repair can achieve equal results of nerve regeneration compared to an end-to-end repair using donor phrenic nerves in repair of the musculocutaneous nerve and also pulmonary protection. Eighteen rats were divided into three groups of six each comparing two nerve graft techniques: helicoid end-to-side plus distal oblique repair vs. traditional end-to-end repair, using a donor phrenic nerve. The saphenous nerve was used as a graft between the phrenic nerve and the musculocutaneous nerve. The third group was used as control; the musculocutaneous nerve was transected without any repair. Three months postoperatively, electrophysiology, tetanic force, moist muscle weight, histology, nerve fiber counting, and chest X-ray were evaluated. All results have shown that this modified end-to-side repair was superior to the end-to-end repair. The former did not compromise the diaphragm function, but the latter showed an elevation of the diaphragm. Little recovery was seen in the third group. The conclusion is that this modified end-to-side repair can replace the traditional end-to-end repair using donor phrenic nerves with better results of nerve regeneration without diaphragm compromise.

Author List

Yan YH, Yan JG, Matloub HS, Zhang LL, Hettinger P, Sanger J, Jaradeh SS

Author

Hani S. Matloub MD Professor in the Plastic Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Diaphragm
Electrodiagnosis
Femoral Nerve
Isometric Contraction
Male
Microsurgery
Muscle, Skeletal
Musculocutaneous Nerve
Nerve Regeneration
Nerve Transfer
Phrenic Nerve
Radiography
Rats
Rats, Sprague-Dawley
Treatment Outcome