Flow Cytometry of B-Cell Neoplasms. Clin Lab Med 2017 Dec;37(4):697-723
Date
11/13/2017Pubmed ID
29128065DOI
10.1016/j.cll.2017.07.001Scopus ID
2-s2.0-85028626763 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
Flow cytometric evaluation is considered a standard ancillary study for the diagnosis of most B-cell lymphoproliferative disorders. Establishing a neoplastic B-cell population depends on identification of light chain restriction or lack of light chain expression in mature neoplasms and demonstration of aberrant antigen expression in both immature and mature neoplasms, as compared with normal counterparts. The immunophenotypes of the most common B-cell neoplasms are herein described, with an emphasis on their immunophenotypic differential diagnosis and prognostic and therapeutic implications.
Author List
Kroft SH, Harrington AMAuthors
Alexandra M. Harrington MD Professor in the Pathology department at Medical College of WisconsinSteven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Flow CytometryHumans
Immunophenotyping
Lymphoma, B-Cell