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Flow Cytometry of B-Cell Neoplasms. Clin Lab Med 2017 12;37(4):697-723

Date

11/13/2017

Pubmed ID

29128065

DOI

10.1016/j.cll.2017.07.001

Scopus ID

2-s2.0-85028626763   9 Citations

Abstract

Flow cytometric evaluation is considered a standard ancillary study for the diagnosis of most B-cell lymphoproliferative disorders. Establishing a neoplastic B-cell population depends on identification of light chain restriction or lack of light chain expression in mature neoplasms and demonstration of aberrant antigen expression in both immature and mature neoplasms, as compared with normal counterparts. The immunophenotypes of the most common B-cell neoplasms are herein described, with an emphasis on their immunophenotypic differential diagnosis and prognostic and therapeutic implications.

Author List

Kroft SH, Harrington AM

Authors

Alexandra M. Harrington MD Professor in the Pathology department at Medical College of Wisconsin
Steven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Flow Cytometry
Humans
Immunophenotyping
Lymphoma, B-Cell