Gastrointestinal motility: some basic concepts. Pharmacology 1988;36 Suppl 1:7-14
Date
01/01/1988Pubmed ID
3285364DOI
10.1159/000138415Scopus ID
2-s2.0-0023852827 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
The spatial and temporal patterns of phasic contractions in the gastrointestinal tract are regulated by a complex interplay between the myogenic, neural and chemical control mechanisms. These contractions are largely responsible for the mixing and propulsive movements of the gut after a meal. In the fasted state, organized groups of contractions called cyclic motor activity and migrating motor complex keep the upper digestive tract clean of residual food and debris. In addition, the small intestine and the colon generate giant migrating contractions which are several-fold stronger than the postprandial phasic contractions and migrate uninterrupted over long distances. The giant migrating contractions are effective in rapid propulsion. The upper small intestine and the antrum generate retrograde giant contractions that generally precede vomiting.
Author List
Sarna SK, Otterson MFAuthor
Mary F. Otterson MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsDigestive System Physiological Phenomena
Dogs
Gastrointestinal Motility
Humans
Muscle Contraction
