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Immunologic and Virologic Outcomes of Obese and Nonobese Incarcerated Adults on Antiretroviral Therapy for HIV Infection. J Int Assoc Provid AIDS Care 2018;17:2325957417752261

Date

01/24/2018

Pubmed ID

29357770

Pubmed Central ID

PMC6748539

DOI

10.1177/2325957417752261

Scopus ID

2-s2.0-85059112546

Abstract

BACKGROUND: Obesity is common among patients with HIV. The objective of this study was to characterize response to antiretroviral therapy (ART) in a cohort of obese incarcerated adults compared to a nonobese cohort.

METHODS: A retrospective matched cohort study was conducted in an HIV telemedicine clinic. Patients with body mass index (BMI) >30 kg/m2 who received the same ART with >95% adherence for at least 6 months were matched to nonobese patients by age, gender, ART, CD4 count, and viral load at baseline.

RESULTS: Twenty pairs were included, with an average BMI of 24 kg/m2 in the nonobese cohort and 35 kg/m2 in the obese cohort. No difference was observed in the proportion of patients who achieved virologic suppression or the change in CD4 count from baseline to 6 to 12 months.

CONCLUSION: This study revealed no differences in immunologic recovery or virologic suppression between obese and nonobese patients in an adult correctional population.

Author List

Bunnell KL, Aldossari A, Perkins C, Schriever C, Chiampas TD, Young JD, Patel MC, Badowski M

Author

Kristen B. Bresnehan PharmD Assistant Professor in the School of Pharmacy Administration department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Anti-HIV Agents
Body Mass Index
CD4 Lymphocyte Count
Female
HIV Infections
HIV-1
Humans
Male
Middle Aged
Obesity
Prisoners
Retrospective Studies
Viral Load