Faculty Collaboration Database

Prostate cancer: genes, environment, immunity and the use of immunotherapy. Prostate Cancer Prostatic Dis 2008;11(3):230-6

Date

02/20/2008

Pubmed ID

18283297

DOI

10.1038/pcan.2008.3

Scopus ID

2-s2.0-50649089095 (requires institutional sign-in at Scopus site)   26 Citations

Abstract

Prostate cancer remains the most prevalent noncutaneous cancer, leading to almost 30,000 deaths every year in men in the United States. A large body of knowledge emphasizes a strong influence of epidemiological factors such as lifestyle, environment and diet, on the development of prostate cancer. Although risk reduction of prostate cancer has been somewhat successful, effective prevention is still lacking. Immunotherapeutic approaches, although moderately complicated, remain promising in an effort to control the progression and development of the disease. Taken together, the parameters of epidemiological studies and immunotherapeutic regimens might eventually be the most effective and preventive approach for prostate cancer. This review highlights some of the events associated with the development and prevention of prostate cancer.

Author List

Karan D, Thrasher JB, Lubaroff D

Author

Dev Karan PhD Associate Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Antineoplastic Agents
Cancer Vaccines
Disease Progression
Environment
Humans
Immune System
Immunotherapy
Male
Models, Biological
Prostatic Neoplasms
Risk Factors
Toll-Like Receptor 9