Faculty Collaboration Database

Central ECMO for circulatory failure following pediatric liver transplantation. Perfusion 2018 Nov;33(8):704-706

Date

05/24/2018

Pubmed ID

29788811

DOI

10.1177/0267659118778170

Scopus ID

2-s2.0-85047387016 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

We describe the case of a 4-year-old male with a past medical history significant for nephrotic syndrome, short-bowel syndrome and fulminant hepatic failure status post (s/p) liver transplant (LT) who developed early post-transplant allograft dysfunction (hyperbilirubinemia, coagulopathy) and septic shock requiring central extracorporeal membrane oxygenation (ECMO). He remained on ECMO for 85 hours before he was decannulated without event and later underwent repeat LT. This case highlights the potential of central ECMO to provide the circulatory output necessary to reverse distributive shock physiology in patients with sepsis and hepatic dysfunction following LT. Furthermore, this is the first documented example of central ECMO as a bridge to recovery for repeat LT.

Author List

Scott JP, Hong JC, Thompson NE, Woods RK, Hoffman GM

Authors

George M. Hoffman MD Chief, Professor in the Anesthesiology department at Medical College of Wisconsin
John P. Scott MD Professor in the Anesthesiology department at Medical College of Wisconsin
Nathan Thompson MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Ronald K. Woods MD Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Child, Preschool
Extracorporeal Membrane Oxygenation
Humans
Liver Failure, Acute
Liver Transplantation
Male
Nephrotic Syndrome
Shock
Short Bowel Syndrome
Time Factors