Faculty Collaboration Database

Examination of the Role of Religious and Psychosocial Factors in HIV Medication Adherence Rates. J Relig Health 2017 Dec;56(6):2144-2161

Date

03/13/2017

Pubmed ID

28285439

Pubmed Central ID

PMC9897031

DOI

10.1007/s10943-017-0377-1

Scopus ID

2-s2.0-85014964368 (requires institutional sign-in at Scopus site)   22 Citations

Abstract

Optimal adherence to antiretroviral therapy (ART) is associated with favorable HIV outcomes, including higher CD4 cell counts, HIV virus suppression and a lower risk of HIV transmission. However, only 25% of people living with HIV/AIDS (PLWH) in the USA are virally suppressed. Sub-optimal adherence (<90-95%) contributes to antiretroviral resistance and worse medical outcomes, including more rapid progression to AIDS and death. Psychosocial factors and religion/spirituality (R/S) have a significant impact on ART adherence, but the findings are mixed. The purpose of this study was to examine religious and psychosocial correlates and predictors of ≥90% ART adherence in PLWH. A cross-sectional study was conducted with a sample of 292 outpatient PLWH in the Southeastern USA. Participants completed computerized surveys. The mean ART adherence percentage was 80.9% and only about half reported ≥90% adherence. There were statistically significant differences in ART adherence rates based on age, depressive symptom status and frequency of religious attendance and prayer. Praying at least once a day was significantly associated with ≥90% ART adherence (OR = 2.26, 95% CI [1.06-4.79], p < 0.05). Social support satisfaction was also significantly associated with ART adherence (OR = 1.52, 95% CI [1.11-2.08], p < 0.05) and energy/fatigue/vitality (OR = 1.03, 95% CI [1.00-1.05], p < 0.05).

Author List

Dalmida SG, McCoy K, Koenig HG, Miller A, Holstad MM, Thomas T, Clayton-Jones D, Grant M, Fleming T, Wirani MM, Mugoya G

Author

Dora Clayton-Jones PhD RN CPNP-PC Assistant Professor in the College of Nursing department at Marquette University

MESH terms used to index this publication - Major topics in bold

Anti-HIV Agents
Cross-Sectional Studies
Female
HIV Infections
Humans
Male
Medication Adherence
Middle Aged
Religion and Medicine
Social Support
Southeastern United States