Genital human papillomavirus (HPV) concordance in heterosexual couples. J Infect Dis 2012 Jul 15;206(2):202-11
Date
04/28/2012Pubmed ID
22539815Pubmed Central ID
PMC3490693DOI
10.1093/infdis/jis327Scopus ID
2-s2.0-84862849828 (requires institutional sign-in at Scopus site) 35 CitationsAbstract
BACKGROUND: Few studies have assessed genital human papillomavirus (HPV) concordance and factors associated with concordance among asymptomatic heterosexual couples.
METHODS: Genotyping for HPV was conducted with male and female sex partners aged 18-70 years from Tampa, Florida. Eligibility included no history of HPV-associated disease. Type-specific positive concordance (partners with ≥ 1 genotype in common) and negative concordance (neither partner had HPV) were assessed for 88 couples. Factors associated with concordance were assessed with Fisher exact tests and tests for trend.
RESULTS: Couples reported engaging in sexual intercourse for a median of 1.7 years (range, 0.1-49 years), and 75% reported being in the same monogamous relationship for the past 6 months. Almost 1 in 4 couples had type-specific positive concordance, and 35% had negative concordance for all types tested, for a total concordance of 59%. Concordance was not associated with monogamy. Type-specific positive concordance was associated with an increasing difference in partners' lifetime number of sex partners and inversely associated with an increasing difference in age. Negative concordance was inversely associated with both the couple's sum of lifetime number of sex partners and the difference in the partners' lifetime number of sex partners.
CONCLUSIONS: Genital HPV concordance was common. Viral infectiousness and number of sex partners may help explain concordance among heterosexual partners.
Author List
Nyitray AG, Menezes L, Lu B, Lin HY, Smith D, Abrahamsen M, Papenfuss M, Gage C, Giuliano ARAuthor
Alan Nyitray PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Aged
Alphapapillomavirus
Condylomata Acuminata
Female
Genotype
Heterosexuality
Humans
Male
Middle Aged
Sexual Partners
Young Adult
