Human papillomavirus type distribution among heterosexual couples. J Low Genit Tract Dis 2012 Jan;16(1):10-5
Date
10/04/2011Pubmed ID
21964207DOI
10.1097/LGT.0b013e31822a8404Scopus ID
2-s2.0-84855339737 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
OBJECTIVE: To gain a better understanding of human papillomavirus (HPV) transmission dynamics between sexual partners, HPV-type-specific concordance was investigated.
METHODS: Twenty-nine couples were enrolled in this cross-sectional study. Mean age was 30.5 years (range = 19.1-42.6 y) for men and 28.2 years (range = 19.4-44.5 y) for women. Samples were collected at the glans penis, penile shaft, and scrotum in men and at the endo/ectocervix and labia/vulva, and perineum in women. Samples were analyzed for the presence of HPV DNA first by polymerase chain reaction and then genotyped using the reverse-line blot method.
RESULTS: Human papillomavirus prevalence for any HPV type was 75.9% among men and 86.2% among women. Eleven men and 10 women were infected with multiple HPV types. At least partial type-specific concordance was observed in 66% of the couples. Forty-one percent of the couples had perfect concordance. In 11 couples (37.9%), complete discordance was observed.
CONCLUSIONS: These results provide valuable information about HPV-type-specific concordance and demonstrate the complexity of transmission dynamics in heterosexual couples.
Author List
Abalos AT, Harris RB, Nyitray AG, Mitchell A, Thompson PA, Giuliano AR, Garcia FAuthor
Alan Nyitray PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultCross-Sectional Studies
DNA, Viral
Female
Genitalia, Female
Genitalia, Male
Genotype
Heterosexuality
Humans
Male
Middle Aged
Papillomaviridae
Papillomavirus Infections
Polymerase Chain Reaction
Prevalence
Sexual Partners
Surveys and Questionnaires
Young Adult
