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Positive 2-Tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the United States. Pediatr Infect Dis J 2019 May;38(5):e105-e107

Date

08/02/2018

Pubmed ID

30067595

Pubmed Central ID

PMC6355375

DOI

10.1097/INF.0000000000002157

Scopus ID

2-s2.0-85062407421 (requires institutional sign-in at Scopus site)   10 Citations

Abstract

Knowing the frequency of positive Lyme disease serology in children without signs of infection facilitates test interpretation. Of 315 asymptomatic children from Lyme disease endemic regions, 32 had positive or equivocal C6 enzyme-linked immunoassays, but only 5 had positive IgG or IgM supplemental immunoblots (1.6%; 95% confidence interval: 0.7%-3.7%).

Author List

Garro A, Bennett J, Balamuth F, Levas MN, Neville D, Branda JC, Maulden AB, Lantos PM, Nigrovic LE, Pedi Lyme Net

Author

Michael Levas MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Antibodies, Bacterial
Asymptomatic Diseases
Borrelia
Child
Child, Preschool
Female
Humans
Immunoenzyme Techniques
Infant
Lyme Disease
Male
Seroepidemiologic Studies
United States
Young Adult