Synchronous pancreatic tumors in a patient with history of Wilms tumor: A case of pancreatic adenocarcinoma and lipid-rich neuroendocrine tumor diagnosed by cytopathology. Diagn Cytopathol 2018 Oct;46(10):864-869
Date
09/09/2018Pubmed ID
30194916DOI
10.1002/dc.23978Scopus ID
2-s2.0-85052923856 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Synchronous tumors represent a very small portion of pancreatic tumors. Although there is a higher incidence of secondary malignant neoplasms (SMN) in patients with history of Wilms tumor (WT), pancreatic tumors are very infrequent SMNs in this population. We report the first case of synchronous pancreatic tumors in a patient with history of WT. Two separated pancreatic lesions were identified by abdominal computerized tomography (CT) scan. Fine-needle aspiration of both lesions was performed for cytopathology examination. A pancreatic adenocarcinoma was diagnosed in the head of pancreas, and the pancreatic body lesion was found to be a neuroendocrine tumor (NET). The NET had characteristic vacuolated lipid-rich cytoplasm. Further molecular testing was done on both tumors, but no common cancer-associated mutation was found.
Author List
Huang H, Giorgadze TAuthor
Tamara Giorgadze MD Professor in the Pathology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdenocarcinomaCytodiagnosis
Humans
Lipids
Male
Middle Aged
Neoplasms, Multiple Primary
Neuroendocrine Tumors
Pancreatic Neoplasms
Tomography, X-Ray Computed
Wilms Tumor
