Variability in 28-day outcomes for very low birth weight infants: an analysis of 11 neonatal intensive care units. Pediatrics 1988 Oct;82(4):554-9
Date
10/01/1988Pubmed ID
3273485Scopus ID
2-s2.0-0023813773 (requires institutional sign-in at Scopus site) 122 CitationsAbstract
A retrospective study of all infants weighing 701 to 1,500 g born at 11 neonatal intensive care centers during 1983 and 1984 was performed to determine whether two specific 28-day outcomes, survival and survival without the need for supplemental oxygen, varied among the centers. Survival without the need for supplemental oxygen was chosen as a reflection of infants surviving without chronic lung disease. There were 1,776 live-born infants delivered during the 2-year study period. Of these infants, 85% (1,512) survived 28 days, a range of 80% to 92% at the individual centers. A total of 60% (1,056) of the infants were alive without supplemental oxygen on day 28, a range of 51% to 70% at the individual centers. Multivariate analysis demonstrated that both survival on day 28 (chi 2 = 23.9, P less than .01) and survival without supplemental oxygen on day 28 (chi 2 = 44.2, P less than .0001) varied significantly among centers after the effects of birth weight, gender, and race were taken into account. Female gender, nonwhite race, and increased birth weight were factors associated with improved rates of survival and survival without supplemental oxygen. The magnitude of outcome variation among centers was estimated by using the logistic regression models to predict what the outcomes would be if each center were to treat a standardized population consisting of all 1,776 study infants.(ABSTRACT TRUNCATED AT 250 WORDS)
Author List
Horbar JD, McAuliffe TL, Adler SM, Albersheim S, Cassady G, Edwards W, Jones R, Kattwinkel J, Kraybill EN, Krishnan VAuthor
Timothy L. McAuliffe PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Birth WeightBronchopulmonary Dysplasia
Canada
England
Female
Humans
Infant, Low Birth Weight
Infant, Newborn
Infant, Newborn, Diseases
Intensive Care Units, Neonatal
Male
Oxygen
Respiration, Artificial
Sex Factors
United States
