The superior longitudinal fasciculus and speech arrest. J Comput Assist Tomogr 2008;32(3):410-4
Date
06/04/2008Pubmed ID
18520547DOI
10.1097/RCT.0b013e318157c5ffScopus ID
2-s2.0-45849103118 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
We present a 59-year-old woman with recurrent glioblastoma multiforme involving the left medial frontal and cingulate gyri. Diffusion tensor imaging (DTI) showed inferior-lateral tumor border proximity to the superior-medial (supracallosal) portion of the left frontal superior longitudinal fasciculus (SLF). Dissections of the tumor border contacting the dominant SLF caused speech arrests 8 times, with full recovery. At postoperative day 2, edema caused transient mild aphasia and paraphasic errors. Postoperative DTI showed an inferior-lateral resection cavity in immediate proximity to the supracallosal aspect of the left SLF. The case demonstrates excellent correlation between tumor border proximity to the dominant SLF shown at DTI and speech deficits caused by intraoperative dissections and postoperative edema. The case is the first to demonstrate speech arrest associated with lesion proximity to the supracallosal aspect of the SLF. Other SLF-related deficits are reviewed.
Author List
Davtian M, Ulmer JL, Mueller WM, Gaggl W, Mulane MP, Krouwer HGAuthor
Wade M. Mueller MD Professor in the Neurosurgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Brain NeoplasmsDiffusion Magnetic Resonance Imaging
Female
Glioblastoma
Gyrus Cinguli
Humans
Middle Aged
Patient Care Planning
Speech Disorders
