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The development of ascending aortic aneurysms after elective aortic valve replacement with St Jude mechanical valve prosthesis in the bicuspid patient: a pilot study. Angiology 2013 Jul;64(5):379-84



Pubmed ID




Scopus ID

2-s2.0-84878359480   2 Citations


The association between bicuspid aortic valve (BAV) and ascending aorta aneurysm is well described. Replacement of the ascending aorta is now being considered at 4.5 cm. We identified patients confirmed with BAV who underwent elective aortic valve replacement (AVR) with a mechanical St Jude Bioprosthesis from 1994 to 2000 who were ≤65 years of age at the time of surgery. Follow-up imaging was obtained by computed tomography (CT) angiography or echocardiography. A total of 225 patients who underwent AVR were identified; 60 patients had a BAV. Of all, 36 (60%) patients with BAV returned for follow-up imaging of their ascending aorta. Eight patients (22%) had diameters classifiable as aneurysmal (>4.5 cm) that developed within 9.6 ± 4.1 years from implant and requiring surgery. Of all, 7 patients (12%) died within 5.9 ± 2.5 years from their implant date. Lifelong serial monitoring of the ascending aorta for patients with BAV should be the standard of care.

Author List

Cohoon KP, Foley J, Dieter RS, Bakhos M, Schwartz J


Kevin Cohoon DO Assistant Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aortic Aneurysm
Aortic Valve
Cohort Studies
Elective Surgical Procedures
Heart Valve Diseases
Heart Valve Prosthesis
Heart Valve Prosthesis Implantation
Middle Aged
Pilot Projects
Treatment Outcome