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Effect of dietary vitamin E on the production of platelet 12-hydroxyeicosatetraenoic acid (12-HETE). Thromb Haemost 1986 Feb 28;55(1):6-7

Date

02/28/1986

Pubmed ID

3705009

Abstract

Collagen and thrombin challenged platelets from vitamin E-deficient rabbits generated significantly more 12-HETE when compared to the platelets from vitamin E-supplemented rabbits. Similarly, conversion of arachidonic acid to 12-HETE was increased in platelets from vitamin E-deficient rabbits. These data show that vitamin E plays a role not only in deacylation of platelet phospholipids but also in the lipoxygenase mediated reactions.

Author List

Pritchard KA, Greco NJ, Panganamala RV

Author

Kirkwood A. Pritchard PhD Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
Animals
Blood Platelets
Collagen
Hydroxyeicosatetraenoic Acids
In Vitro Techniques
Male
Rabbits
Thrombin
Vitamin E
Vitamin E Deficiency
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