A 17-Year-Old Boy With Right Face Palsy, Left Leg Weakness, and Lytic Skull-Bone Lesions. J Pediatric Infect Dis Soc 2018 Dec 03;7(4):350-354
Date
01/27/2018Pubmed ID
29373673Pubmed Central ID
PMC6276027DOI
10.1093/jpids/pix101Scopus ID
2-s2.0-85058750832 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Human T-cell lymphotropic virus (HTLV), an infection that is endemic in certain parts of Asia, Africa, and South America, has been associated with malignancy and neurological deficits. Here, we describe a pediatric patient with chronic HTLV-I infection who developed complications associated with HTLV-I (ie, adult T-cell leukemia/lymphoma and HTLV-I-associated myelopathy/tropical spastic paraparesis). To our knowledge, this presentation in a child has never been described. The patient underwent a bone marrow transplant and, at the time of this writing, was in remission. This case report highlights the fact that HTLV-related complications, previously expected to occur after decades of infection, also can occur in pediatric patients, particularly those who acquired HTLV-I perinatally.
Author List
Akinboyo IC, Crane GM, Chen L, Arav-Boger RAuthor
Ravit Boger MD Chief, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAntiviral Agents
Bell Palsy
Bone Marrow Transplantation
Chronic Disease
Cranial Irradiation
Deltaretrovirus Infections
Diagnosis, Differential
Endemic Diseases
Hearing Loss, Bilateral
Humans
Leg
Male
Muscle Weakness
Radiography
Skull
Tomography, X-Ray Computed
