Cytomegalovirus Enterocolitis in Immunocompetent Young Children: A Report of Two Cases and Review of the Literature. Pediatr Infect Dis J 2016 May;35(5):573-6
Date
02/11/2016Pubmed ID
26862673Pubmed Central ID
PMC4829454DOI
10.1097/INF.0000000000001080Scopus ID
2-s2.0-84957824110 (requires institutional sign-in at Scopus site) 14 CitationsAbstract
Cytomegalovirus (CMV) causes significant morbidity and mortality in congenitally infected children and immunocompromised hosts. Among healthy individuals, CMV is generally thought to cause mild, self-limited illness. CMV enterocolitis, in particular, is rarely considered among immunocompetent children presenting with diarrhea. We describe 2 cases of invasive CMV colitis in immunocompetent infants presenting with diarrhea and review the literature to date on this topic. Although invasive CMV enterocolitis has been sporadically reported among immunocompetent children, it remains an underrecognized cause of infectious diarrhea in this population and indications for antiviral therapy are lacking. We propose that CMV should be included in the differential diagnosis of intractable diarrhea in immunocompetent children.
Author List
Sue PK, Salazar-Austin NM, McDonald OG, Rishi A, Cornish TC, Arav-Boger RAuthors
Ravit Boger MD Chief, Professor in the Pediatrics department at Medical College of WisconsinToby Charles Cornish MD Professor in the Pathology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
CytomegalovirusCytomegalovirus Infections
Diarrhea
Enterocolitis
Humans
Infant
Male
