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[Decreased interleukin-1 and interleukin-2 production after splenectomy]. Harefuah 1994 Apr 01;126(7):374-7, 426

Date

04/01/1994

Pubmed ID

8200582

Scopus ID

2-s2.0-0028411285 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.

Author List

Spirer Z, Arav-Boger R, Zakuth V, Tzehoval E, Dagan S, Lev B, Golander A, Melamed I

Author

Ravit Boger MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Age Factors
Female
Humans
Interleukin-1
Interleukin-2
Male
Splenectomy
Time Factors