[Decreased interleukin-1 and interleukin-2 production after splenectomy]. Harefuah 1994 Apr 01;126(7):374-7, 426
Date
04/01/1994Pubmed ID
8200582Scopus ID
2-s2.0-0028411285 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.
Author List
Spirer Z, Arav-Boger R, Zakuth V, Tzehoval E, Dagan S, Lev B, Golander A, Melamed IAuthor
Ravit Boger MD Chief, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Age Factors
Female
Humans
Interleukin-1
Interleukin-2
Male
Splenectomy
Time Factors