Generation of phases I and II of migrating myoelectric complex in the dog. Am J Physiol 1986 Aug;251(2 Pt 1):G201-7
Date
08/01/1986Pubmed ID
3740263DOI
10.1152/ajpgi.1986.251.2.G201Scopus ID
2-s2.0-0022511999 (requires institutional sign-in at Scopus site) 20 CitationsAbstract
The mechanisms of generation of most of the phases of the migrating myoelectric complex (MMC) are unclear. Except for phase III activity, this issue has not been investigated directly. We have qualitatively examined the relations between different phases of the MMC cycle in order to provide an objective basis for the formation of theories. Eight dogs of either sex were implanted with 10 bipolar electrodes distributed along the gastrointestinal tract. Myoelectric activity was recorded during the fasted state or after feeding until the return of the MMC cycle. The relations between phase I duration, phase II duration, phase III migration time, and phase III period were examined using simple linear-regression methods. We found that only phase I duration was highly correlated (r = 0.87, P less than 0.01) with phase III migration time and that only phase II duration was highly correlated (r = 0.90, P less than 0.01) with phase III period. In either the fed or fasted state, phase III activity that began in the midjejunum was accompanied concurrently with phase I activity of the duodenum and upper jejunum, where phase III activity had not occurred. Also, the position of phase III activity in the lower small intestine when phase I activity of the upper small intestine ended was 277 +/- 24 cm (83 +/- 5% of the small intestinal length) from the pylorus, and the coefficient of variation of this position was significantly smaller (P less than 0.01) than that of the other cycle variables.(ABSTRACT TRUNCATED AT 250 WORDS)
Author List
Lang IM, Sarna SK, Condon REAuthor
Ivan M. Lang DVM, PhD Adjunct Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsDogs
Duodenum
Electrodes, Implanted
Feedback
Female
Gastrointestinal Motility
Male
Muscle Contraction
Muscle, Smooth
Stomach
Time Factors
