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Case report: Delayed enhancement on cardiac MRI in a patient with multiple myeloma without amyloidosis. Br J Radiol 2008 Nov;81(971):e272-5

Date

10/23/2008

Pubmed ID

18941041

DOI

10.1259/bjr/58586915

Scopus ID

2-s2.0-55249089219 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

We report the first observation of diffuse subendocardial and myocardial delayed enhancement on cardiac MRI in a 50-year-old patient with recurrent multiple myeloma but without evidence of amyloidosis. She presented with advanced heart failure and severe restrictive cardiomyopathy. Myocardial biopsy revealed endomyocardial fibrosis. The case was associated with development of multiple arterial and venous thromboses and a fatal course. Because of the fatal outcome, the prognostic significance of delayed enhancement on MRI in multiple myeloma patients may need to be further investigated.

Author List

Brahmbhatt T, Hari P, Cinquegrani M, Kumar N, Komorowski R, Migrino RQ

Authors

Michael P. Cinquegrani MD Director, Professor in the Medicine department at Medical College of Wisconsin
Parameswaran Hari MD Adjunct Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Cardiomyopathy, Restrictive
Contrast Media
Endomyocardial Fibrosis
Fatal Outcome
Female
Gadolinium DTPA
Heart Failure
Humans
Magnetic Resonance Imaging
Middle Aged
Multiple Myeloma
Thrombosis