Case report: Delayed enhancement on cardiac MRI in a patient with multiple myeloma without amyloidosis. Br J Radiol 2008 Nov;81(971):e272-5
Date
10/23/2008Pubmed ID
18941041DOI
10.1259/bjr/58586915Scopus ID
2-s2.0-55249089219 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
We report the first observation of diffuse subendocardial and myocardial delayed enhancement on cardiac MRI in a 50-year-old patient with recurrent multiple myeloma but without evidence of amyloidosis. She presented with advanced heart failure and severe restrictive cardiomyopathy. Myocardial biopsy revealed endomyocardial fibrosis. The case was associated with development of multiple arterial and venous thromboses and a fatal course. Because of the fatal outcome, the prognostic significance of delayed enhancement on MRI in multiple myeloma patients may need to be further investigated.
Author List
Brahmbhatt T, Hari P, Cinquegrani M, Kumar N, Komorowski R, Migrino RQAuthors
Michael P. Cinquegrani MD Director, Professor in the Medicine department at Medical College of WisconsinParameswaran Hari MD Adjunct Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Cardiomyopathy, RestrictiveContrast Media
Endomyocardial Fibrosis
Fatal Outcome
Female
Gadolinium DTPA
Heart Failure
Humans
Magnetic Resonance Imaging
Middle Aged
Multiple Myeloma
Thrombosis