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Mesh term Certolizumab Pegol

Browse to parent terms:
Antibodies, Monoclonal, Humanized
Immunoglobulin Fab Fragments
Polyethylene Glycols


A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.

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