Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Certolizumab Pegol

Browse to parent terms:
Antibodies, Monoclonal, Humanized
Immunoglobulin Fab Fragments
Polyethylene Glycols

Description

A polyethylene-glycolated Fab' fragment of TUMOR NECROSIS FACTOR antibody that binds specifically to TNF-ALPHA and neutralises it in a dose-dependent manner. It also inhibits the production of lipopolysaccharide-induced TNF-ALPHA and IL-1 BETA and is used to treat RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.



Search for this term in our Faculty Database



View this term at the NCBI website