Mesh term Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Browse to parent terms:Nuclear Receptor Coactivators
RNA Recognition Motif Proteins
Description
A transcriptional co-activator for NUCLEAR RECEPTORS. It is characterized by an N-terminal LxxLL sequence, a region that interacts with PPAR GAMMA, and a C-terminal RNA RECOGNITION MOTIF. It increases expression of MITOCHONDRIAL UNCOUPLING PROTEIN to regulate genes involved in metabolic reprogramming in response to dietary restriction and the integration of CIRCADIAN RHYTHMS with ENERGY METABOLISM.Search for this term in our Faculty Database
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