Mesh term Transcription Factor HES-1
Browse to parent terms:Basic Helix-Loop-Helix Transcription Factors
Description
A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.Search for this term in our Faculty Database
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