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Mesh term T-Cell Acute Lymphocytic Leukemia Protein 1

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Basic Helix-Loop-Helix Transcription Factors
Proto-Oncogene Proteins


A basic helix-loop-helix transcription factor that plays a critical role in HEMATOPOIESIS and as a positive regulator in the differentiation of ERYTHROID CELLS. Chromosome translocations involving the TAL-1 gene are associated with T-CELL ACUTE LYMPHOCYTIC LEUKEMIA.

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