Mesh term CCCTC-Binding Factor
Browse to parent terms:Chromosomal Proteins, Non-Histone
DNA-Binding Proteins
Poly-ADP-Ribose Binding Proteins
Repressor Proteins
Description
A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.Search for this term in our Faculty Database
View this term at the NCBI website
