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Mesh term Myristoylated Alanine-Rich C Kinase Substrate

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Calmodulin-Binding Proteins
Intracellular Signaling Peptides and Proteins
Membrane Proteins
Microfilament Proteins
Poly-ADP-Ribose Binding Proteins


A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.

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