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Mesh term Burkitt Lymphoma

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Epstein-Barr Virus Infections
Lymphoma, B-Cell

Description

A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.



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jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14