Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Tourette Syndrome

Browse to parent terms:
Basal Ganglia Diseases
Heredodegenerative Disorders, Nervous System
Tic Disorders

Description

A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or a another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)



Search for this term in our Faculty Database



View this term at the NCBI website